MO
re Connections:
Business & Innovation Ecosystem
Where Big Ideas Belong
— and Businesses Grow
Columbia’s economy has always been rooted in education, healthcare, and service — but today, it’s also driven by innovation, entrepreneurship, and a thriving community of people building what’s next. Whether you’re launching a company, joining a high-growth team, or looking to invest in a place with momentum, Columbia offers more support, more talent, and more room to grow.
Columbia’s Economic Landscape At-A-Glance
Top Employers:
University of Missouri, MU Health Care, Veterans United Home Loans, EquipmentShare, and Boone Health
Startups & Growth Companies:
Dozens of high-growth startups in logistics tech, agtech, health innovation, and software
Innovation & R&D:
Anchored by a Tier 1 research university (Mizzou), multiple medical research centers, and tech incubators
Major Industries:
- Healthcare & Life Sciences
- Education & Research
- Technology & Software
- Advanced Manufacturing
- Finance & Real Estate
- Construction Tech & Logistics
Columbia’s unemployment rate remains below the national average , and the region’s job market is projected to grow by over 30% in the next decade.
— U.S. Bureau of Labor Statistics, Missouri Economic Research & Information Center
Start Something Big — or Join What’s Growing
Columbia is an ideal launchpad for entrepreneurs, creators, and innovators. Here’s why:
-
REDI
(Regional Economic Development Inc.) – Business attraction, expansion, and funding support -
Innovation Hub @ MU
Startup resources, coworking, and mentorship -
The Missouri Innovation Center
Incubator for biotech and scalable tech startups -
Columbia Startup Weekend, 1 Million Cups, and CoMo Cooks
Active community-driven events and programs
Startup Success Stories
Veterans United Home Loans
The nation’s largest VA lender with a strong tech culture
EquipmentShare
Building the future of construction and founded in Columbia
Paytient
Helping people across the country make better healthcare decisions by improving their ability to pay for care
Veterans United Home Loans
The nation’s largest VA lender with a strong tech culture
EquipmentShare
Building the future of construction and founded in Columbia
Paytient
Helping people across the country make better healthcare decisions by improving their ability to pay for care
A Collaborative Business Culture
Columbia’s size makes it easier to connect — with local leaders, partners, talent, and capital. You won’t get lost in the crowd here.
Events that bring entrepreneurs, professionals, and civic leaders together regularly
Local chambers and accelerators focused on inclusion and innovation
Access to regional funding sources and angel investor networks
Strong connections between the university and private sector
Great Support Team
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Joseph L.Mabie
Influencer
Columbia — By the Numbers
$325000
Median Home Price, (2025 YTD, CBOR)
0%
Cost of Living - below national avg (C2ER)
0%
unemployment rate (2025) – consistently below the national average
50%
Labor Force Participation
30%
% of Population with Bachelor’s Degree or Higher
1000+
Business Licenses Issued (2024)
0+
minutes average commute time (vs. ~27 minutes nationally)
Ready to Grow in Columbia?
Whether you’re an entrepreneur, executive, or someone looking to return and contribute, Columbia is more connected, more dynamic, and more ready for you than ever before.
Let us help you plug into the people, places, and programs shaping the next chapter of Columbia’s economy.
